Key Bioinformatics Databases
Phil Chapman
2017/10/26
- cBioPortal
- Understand genetic landscape of different tumour types
- ICGC Portal
- International Cancer Genomics Consortium Portal - Understand genetic landscape of different tumour types
- Broad CCLE
- Understand specifics of cell lines - affy, mutations
- Can search for cell lines with a given mutation, can also check BAM file
- Cosmic CLP
- Exome sequencing of cell lines
- Sanger Genomics of Drug Sensitivity
- Eurofins-like cell line sensitivity to drugs
- PharmacoDB
- Collation of Sanger GDS dataset plus a number of others
- PharmacoGx Bioconductor package for further analysis
- Oncomine
- Commercial collection of gene expression datasets - useful for understanding whether a gene is up/down regulated in a cancer type